Randomization in clinical trials : theory and practice

Autor: Rosenberger, William F.
Rok: c2002
ISBN: 9780471236269
OKCZID: 110083653

Citace (dle ČSN ISO 690):
ROSENBERGER, William F. Randomization in clinical trials: theory and practice. New York: Wiley-Interscience, c2002. xvii, 259 s. Wiley series in probability and statistics.

Anotace

A unique overview that melds the concepts of conditional probability and stochastic processes into real-life applications The role of randomization techniques in clinical trials has become increasingly important. This comprehensive guide combines both the applied aspects of randomization in clinical trials with a probabilistic treatment of properties of randomization. Taking an unabashedly non-Bayesian and nonparametric approach to inference, the book focuses on the linear rank test under a randomization model, with added discussion on likelihood-based inference as it relates to sufficiency and ancillarity. Developments in stochastic processes and applied probability are also given where appropriate. Intuition is stressed over mathematics, but not without a clear development of the latter in the context of the former. Providing a consolidated review of the field, the book includes relevant and practical discussions of: The benefits of randomization in terms of reduction of bias Randomization as a basis for inference Covariate-adaptive and response-adaptive randomization Current philosophies, controversies, and new developments With ample problem sets, theoretical exercises, and short computer simulations using SAS, Randomization in Clinical Trials: Theory and Practice is equally useful as a standard textbook in biostatistics graduate programs as well as a reliable reference for biostatisticians in practice.

Zdroj anotace: OKCZ - ANOTACE Z WEBU

Dostupné zdroje

Přidat komentář a hodnocení

Autor komentáře (127.0.0...)

Hodnocení:

• 1
• 2
• 3
• 4
• 5

Text komentáře: