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Alzheimer's Disease: Biology, Diagnosis and Therapeutics | |||||
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Rok: 1997 AnotaceThe past 15 years have witnessed a remarkable increase in our knowledge of the neurobiology of Alzheimers disease, and as new findings occur, the need for sharing and evaluating the information becomes even more important. An indispensable and detailed volume, this book is a nucleus of the latest information, covering all aspects of the neurobiology of Alzheimers disease, its treatment and psychosocial aspects. Over the past two years, since the publication of the last volume, major advances have been made towards understanding the aetiology and the pathogenesis of this disease. These include the discoveries of the genes whose mutations associate with Alzheimers disease in familial cases; the mechanisms of neuronal degeneration and identification of specific steps in the neurodegenerative process that provide targets for therapeutic intervention. This volume also presents advances in the generation of cellular and animal models of ß-amyloid and tau pathology, the two hallmark lesions of Alzheimers disease. The chapters in this book are at the cutting edge of Alzheimers disease research and will be of enormous value not only to Alzheimers disease researchers, but also to neurobiologists, clinicians and caregivers. Dostupné zdroje
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